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Methotrexate
| ITEMS | LIMIT |
| Description | Yellow crystalline powder |
| Identification | IR,UV conform |
| Water | 12.0% Not more than 12.0% |
| Residue on ignition | 0.1% Not more than 0.1% |
| Chromatographic purity | Total:Not more than 2.0% |
| Specific rotation | Individual:Not more than 0.5% |
| +19°- +24° | |
| Organic volatile impurities | Conforms |
| Assay | 98.0-102.0% |
Antineoplastic agents, for a variety of acute leukemia, choriocarcinoma cell carcinoma, malignant mole and psoriasis patients
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